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Local migraine headache treatment study accepting volunteers

Centricity Research (formerly True North Clinical Research) is currently accepting volunteers to participate in a migraine headache research trial.

Millions of people around the world experience migraine headaches. In fact, it is the third most common medical condition across the globe. Here in Canada, an estimated 2.7 million people live with migraine headaches. Severe migraines can interfere with an individual’s ability to function in daily life, yet there are few treatments available.

Centricity Research, previously known as True North Clinical Research, is actively seeking participants who have been diagnosed with chronic or episodic migraine headaches to volunteer in a phase 2 clinical trial with AEON BioPharma, Inc.

The purpose of this trial is to discover whether a new medication, ABP-450, is a safe and effective treatment for preventing migraines. ABP-450 works in a similar way as Botox, which is an approved drug. This study is being conducted at Centricity’s Halifax location.

We’re very excited to be able to work with AEON on this trial.” Explains Heather Rushton, Patient Engagement Supervisor, “We have historically focused mainly on Alzheimers Disease research, but are happy to be branching out into other areas of the central nervous system.”

Participation Includes Injections and Monitoring

For this particular migraine study, those interested will first be screened by the clinical staff at Centricity Research at their Halifax site. If they are eligible for the study and agree to participate, they will receive two sets of injections spaced three months apart. The medication or placebo is injected into the muscles of the face, head, and base of the neck.

Since this is a double-blind study, volunteers will not know if they are receiving a placebo or the ABP-450 medication.

Participants are monitored closely for the duration of the study in order to ensure their safety as well as to collect relevant data regarding the treatment. The study is designed to discover any side effects the drug may cause as well as how effective it is for preventing migraines.

Migraine Headache Study Eligibility

In order to be eligible to participate in this clinical research trial, volunteers must be over 18 years old, be in good health, and have a doctor who has diagnosed and is managing their migraines.

They must also meet the following requirements:

  • Have a one-year history of episodic migraines or chronic migraines. (Chronic migraines means having at least six migraine days each month.)
  • Be available for all 11 clinic visits over a period of approximately 28 weeks.
  • Are not pregnant nor will they become pregnant during the study period.

Participation is purely voluntary, and consent can be withdrawn at any time.

Volunteers are Essential in Medical Research

Volunteers in clinical research trials like this one serve an essential role in medical research. Without them, new treatments for conditions like migraine headaches would not be available for people around the world.

“We are definitely seeking volunteers who meet the criteria listed above,” says Rushton. “Even if you are uncertain, please reach out to us to discuss the study.”

For more information about the ABP-450 migraine study or to find out if you are eligible to participate, call Centricity Research at 1-855-378-8783 or email them at

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